Bernard Bouteille Selected Research

megazol

5/2004	Plasma kinetics and efficacy of oral megazol treatment in Trypanosoma brucei brucei-infected sheep.
1/2004	Megazol combined with suramin improves a new diagnosis index of the early meningo-encephalitic phase of experimental African trypanosomiasis.
1/2003	Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead.

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Bernard Bouteille Research Topics

Disease

10	African Trypanosomiasis (Nagana) 01/2019 - 07/2003
5	Infections 03/2011 - 05/2004
3	Chagas Disease (American Trypanosomiasis) 01/2008 - 01/2003
1	COVID-19 12/2021
1	Encephalitis (Encephalitis, Rasmussen) 05/2009
1	Cachexia 12/2006
1	Trypanosomiasis 12/2006
1	Pruritus (Itching) 01/2006
1	Intestinal Volvulus (Volvulus) 01/2006
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2006
1	Critical Illness (Critically Ill) 11/2005
1	Invasive Candidiasis 11/2005
1	Body Weight (Weight, Body) 01/2004
1	Brain Diseases (Brain Disorder) 04/2003
1	Central Nervous System Infections (Central Nervous System Infection) 01/2003
1	Parasitic Diseases (Parasitic Disease) 01/2003

Drug/Important Bio-Agent (IBA)

3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2021 - 02/2010
3	EnzymesIBA 02/2010 - 09/2005
3	megazolIBA 05/2004 - 01/2003
3	Suramin (Suramin Sodium)IBA 01/2004 - 01/2003
2	ArginaseIBA 07/2013 - 03/2011
2	Pentamidine (NebuPent)FDA LinkGeneric 06/2011 - 04/2003
2	Melarsoprol (Mel B)IBA 06/2011 - 04/2003
2	ChemokinesIBA 05/2009 - 08/2006
2	AntibodiesIBA 12/2006 - 07/2003
2	CytokinesIBA 12/2006 - 01/2006
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 07/2013
1	Messenger RNA (mRNA)IBA 03/2011
1	Proteins (Proteins, Gene)FDA Link 03/2011
1	Protein Isoforms (Isoforms)IBA 03/2011
1	Immunoglobulin M (IgM)IBA 05/2009
1	trans-sialidaseIBA 01/2008
1	ProstaglandinsIBA 12/2006
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2006
1	Methylene Blue (Methylthioninium Chloride)FDA Link 01/2006
1	Nystatin (Mycostatin)FDA LinkGeneric 11/2005
1	ImmunosorbentsIBA 09/2005
1	Biological ProductsIBA 02/2004
1	Nucleosomes (Nucleosome)IBA 07/2003
1	Fas Ligand Protein (Fas Ligand)IBA 07/2003
1	NifurtimoxIBA 04/2003
1	ArsenicIBA 04/2003

Therapy/Procedure

2	Aftercare (After-Treatment) 07/2013 - 01/2004
1	Oral Administration 05/2004
1	Therapeutics 01/2003